Streamlined gram-scale natural N-glycan production using reversible tagging after oxidative release of natural glycans

Abstract The study of natural glycans is fundamental to modern glycomics; however, the functional analysis of these glycans is limited by their low natural abundance, structural heterogeneity, and the absence of efficient preparative-scale isolation methods.Here, we present a streamlined approach for the gram-scale production of complex natural N-g

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Biological Crust Diversity Related to Elevation and Soil Properties at Local Scale in a Montane Scrub of Ecuador

The montane shrublands of southern Ecuador represent one of the least studied ecosystems, which in the last decade have been seriously threatened by increasing wildfires, deforestation, overgrazing, and conversion to forest plantations.Our main objective was to determine, at the local scale, the diversity of species composing the biological soil cr

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Liquid biopsies to occult brain metastasis

Abstract Brain metastasis (BrM) is a major problem associated with cancer-related mortality, and currently, no specific biomarkers are available in clinical settings for early detection.Liquid biopsy Wall Clock is widely accepted as a non-invasive method for diagnosing cancer and other diseases.We have reviewed the evidence that shows how the molec

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